By Kristopher J. Swiger, Joshua R. Thomas, Michael E. Hochman, Steven D. Hochman
50 experiences each Internist should still Know offers key reviews that experience formed the perform of inner medication. chosen utilizing a rigorous method, the reviews conceal themes together with: preventative drugs, endocrinology, hematology and oncology, musculoskeletal ailments, nephrology, gastroenterology, infectious illnesses, cardiology, pulmonology, geriatrics and palliative care, and psychological future health. for every examine, a concise precis is gifted with an emphasis at the effects and obstacles of the examine, and its implications for perform. An illustrative scientific case concludes each one evaluation, via short details on different suitable experiences. This booklet is a must-read for future health care execs and someone who desires to study extra concerning the information at the back of medical perform.
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N Engl J Med. 2009;360(13):1320–1328. 3. Schröder FH et al. Prostate-cancer mortality at 11 years of follow-up. N Engl J Med. 2012;366(11):981–990. 4. Heijnsdijk EA et al. Quality-of-life effects of prostate-specific antigen screening. N Engl J Med. 2012;367(7):595–605. 5 . Schröder FH, Hugosson J, Roobol MJ, Tammela TL, Zappa M, Nelen V, Kwiatkowski M, Lujan M, Määttänen L, Lilja H, Denis LJ, Recker F, Paez A, Bangma CH, Carlsson S, Puliti D, Villers A, Rebillard X, Hakama M, Stenman UH, Kujala P, Taari K, Aus G, Huber A, van der Kwast TH, van Schaik RH, de Koning HJ, Moss SM, Auvinen A; for the ERSPC Investigators.
2012;367(7):595–605. 5 . Schröder FH, Hugosson J, Roobol MJ, Tammela TL, Zappa M, Nelen V, Kwiatkowski M, Lujan M, Määttänen L, Lilja H, Denis LJ, Recker F, Paez A, Bangma CH, Carlsson S, Puliti D, Villers A, Rebillard X, Hakama M, Stenman UH, Kujala P, Taari K, Aus G, Huber A, van der Kwast TH, van Schaik RH, de Koning HJ, Moss SM, Auvinen A; for the ERSPC Investigators. Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up.
There was no effect of screening on all-cause mortality, though the study was not powered for this analysis. Based on the results of ERSPC and a large US prostate cancer screening trial, guidelines from the US Preventive Services Task Force recommend against routine screening. However, the patient in this vignette is at particularly high risk for developing prostate cancer (African American men, as well as men with a family history of prostate cancer, are at increased risk). For this reason, some experts might advocate screening for this patient.
50 Studies Every Internist Should Know by Kristopher J. Swiger, Joshua R. Thomas, Michael E. Hochman, Steven D. Hochman